An efficient Mukaiyama-aldol reaction

August 16, 2024

• Title:       

  An efficient Mukaiyama-aldol reaction

• Image Source:

  Construction of higly functionalized diazoacetoacentates via catalytic Mukaiyama-Michael reactions

• Mark:

  Scheme 1

• Associated context:

  We recently published an efficient Mukaiyama-aldol reaction between methyl 3-(trialkylsilanoxy)-2-diazo-3-butenoate 19 and both aromatic and aliphatic aldehydes 2  (Scheme 1) catalyzed by scandium(III) triflate.