NBS and TCCA Treatment of Different Cyclohexene-Fused Isoxazoline N-Oxide Derivatives

August 19, 2024

• Title:       

  NBS and TCCA Treatment of Different Cyclohexene-Fused Isoxazoline N-Oxide Derivatives

• Image Source:

  Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N-oxides

• Mark:

  Table 2

• Associated context:

  To pursue this goal, we examined the effect of substitution on the phenyl ring (Table 2). In the case of NBS treatment, the products were obtained in good to excellent yields in the presence of an electron-withdrawing group at the para- and meta-positions of the phenyl ring (entries 1, 3, and 5).