Crystal structure of compound 1c

August 21, 2024

• Title:       

  Crystal structure of compound 1c

• Image Source:

  Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N-oxides

• Mark:

  Figure 2, Scheme 4

• Associated context:

  In our case, to reduce the keto group selectively, we treated the compound 1a with lithium aluminum hydride, and we were pleased to find that 3-hydroxyketoxime  (1c) was formed (Scheme 4 and Figure 2). This result is very important and interesting as it produces a special type of  Baylis−Hillman oxime, which contains a 3-bromo functionality.