Reversal of the antilipolytic effect of prostaglandin E2 by an oxazepine derivative (SC-19220)

Add time:08/19/2019    Source:sciencedirect.com

This study shows that SC-19220 can antagonize PGE2 inhibition of epinephrine stimulated lipolysis in the isolated fat cell. The antagonism appears direct and is not due to the stimulating effect of the compound on lipolysis or its potentiation of the lipolytic action of epinerphrine.

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