Antimicrobial Susceptibility StudyStaggering the administration of Polymyxin B (cas 1404-26-8) and meropenem in time-kill against carbapenem-resistant Enterobacteriaceae exhibiting a wide range of meropenem MICs

Add time:09/09/2019    Source:sciencedirect.com

Little is known regarding the appropriate timing and sequencing of a carbapenem and polymyxin in combination against carbapenem-resistant Enterobacteriaceae. Meropenem and Polymyxin B (cas 1404-26-8) were administered simultaneously or 1 agent 2 h prior to the other, in vitro. The carbapenem should be administered prior to the polymyxin when used in combination.

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