Regioselective chlorination of cellulose esters by Methanesulfonyl chloride (cas 124-63-0)
-
Add time:09/08/2019 Source:sciencedirect.com
Regioselective chlorination of cellulose is challenging due to its low reactivity, the small reactivity differences between cellulosic hydroxyl groups, and the high and diverse reactivity of most common chlorinating agents. Halogenation of cellulose affords useful precursors for subsequent nucleophilic substitution reactions, permitting incorporation of new functionality. Herein we report a simple and efficient pathway for preparation of 6-chloro-6-deoxycellulose esters and their derivatives. Cellulose acetate (degree of substitution (DS) 1.75, CA320S) can be chlorinated by essentially quantitative reaction of the primary alcohol groups with methanesulfonyl chloride (MsCl), yielding 6-chloro-6-deoxy cellulose acetate. Characterization methods including 1H NMR, 13C NMR, FT-IR spectroscopy, and elemental analysis, demonstrated chemo- and regioselective C-6 chlorination. We also demonstrate that chlorinated cellulose acetate is a useful intermediate for displacement reactions with nucleophiles including sodium azide, amines, and thiols to prepare functional cellulose ester derivatives.
We also recommend Trading Suppliers and Manufacturers of Methanesulfonyl chloride (cas 124-63-0). Pls Click Website Link as below: cas 124-63-0 suppliers
Prev:Vibrational analysis of the methyl esters of arsenic, methylarsonic and dimethylarsinic acid
Next:Regular paperThermokinetic investigation of Methanesulfonyl chloride (cas 124-63-0)-water system) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Cytogenetic effects of softwood kraft pulp bleaching effluents and Methanesulfonyl chloride (cas 124-63-0) in Chinese hamster ovary cells09/27/2019
- An efficient β-amino acid cyclodehydration using Methanesulfonyl chloride (cas 124-63-0) to thienamycin intermediate 3-[1-hydroxyethyl]-4-[methoxy carbonylmethyl]-azetidin-2-one09/26/2019
- Facile preparation of chloromethylaryl solid supports using Methanesulfonyl chloride (cas 124-63-0) and Hunig's base09/25/2019
- Sodium insertion into vanadium pentoxide in Methanesulfonyl chloride (cas 124-63-0)–aluminum chloride ionic liquid09/24/2019
- Vibrational spectra of Methanesulfonyl chloride (cas 124-63-0) and Methanesulfonyl chloride (cas 124-63-0)-d309/10/2019
- Regular paperThermokinetic investigation of Methanesulfonyl chloride (cas 124-63-0)-water system09/09/2019
-
Health and Chemical more >
-
Related Products