An efficient β-amino acid cyclodehydration using Methanesulfonyl chloride (cas 124-63-0) to thienamycin intermediate 3-[1-hydroxyethyl]-4-[methoxy carbonylmethyl]-azetidin-2-one
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Add time:09/26/2019 Source:sciencedirect.com
A new process for β-amino acid 1 cyclodehydration to β-lactam 2 using Methanesulfonyl chloride (cas 124-63-0)/ sodium bicarbonate is described.
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