135-13-7Relevant articles and documents
Emission Control of a Pyrene-thioindigo Compound
Saika, Tetsuyuki,Iyoda, Tomokazu,Honda, Kenichi,Shimidzu, Takeo
, p. 591 - 592 (1992)
Two distinct fluorescence modes of a thioindigo compound substituted with two pyrene groups on the 7 and 7' positions were controlled by geometrical photoisomerization of the thioindigo skeleton.
SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME
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Page/Page column 232, (2018/10/19)
The present invention includes novel substituted bicyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention are capsid inhibitors. (Formula I)
A General Way to Construct Arene-Fused Seven-Membered Nitrogen Heterocycles
Bakulina, Olga,Chizhova, Maria,Dar'in, Dmitry,Krasavin, Mikhail
supporting information, p. 362 - 371 (2018/01/27)
Imines react with seven-membered cyclic anhydrides (prepared from the corresponding dicarboxylic acids by a recently discovered in-situ cyclodehydration protocol) by the Castagnoli–Cushman reaction pathway to give privileged seven-membered arene-fused nitrogen-heterocyclic compounds with reagent-controlled diversity of the skeleton and peripheral groups.
An unexpected triethylsilane-triggered rearrangement of thioaurones to thioflavonols under SPPS conditions
Varedian, Miranda,Langer, Vratislav,Bergquist, Jonas,Gogoll, Adolf
supporting information; experimental part, p. 6033 - 6035 (2009/04/11)
Thioaurones are converted to a mixture of thiaindenes and thioflavonols when exposed to reaction conditions employed in SPPS, that is, treatment with trifluoroacetic acid in the presence of triethylsilane.
Chemistry and folding of photomodulable peptides - Stilbene and thioaurone-type candidates for conformational switches
Erdelyi, Mate,Varedian, Miranda,Skoeld, Christian,Niklasson, Ida B.,Nurbo, Johanna,Persson, Asa,Bergquist, Jonas,Gogoll, Adolf
experimental part, p. 4356 - 4373 (2009/02/07)
Optimized synthetic strategies for the preparation of photoswitchable molecular scaffolds based on stilbene or on thioaurone chromophores and their conformationally directing properties, as studied by computations and by NMR spectroscopy, are addressed. For the stilbene peptidomimetics 1, 2 and 3, the length of connecting linkers between the chromophore and the peptide strands was varied, resulting in photochromic dipeptidomimetics with various flexibility. Building blocks of higher rigidity, based on para-substituted thioaurone (4 and 6) and meta-substituted thioaurone chromophores (5 and 7) are shown to have a stronger conformationally directing effect. Design, synthesis, theoretical and experimental conformational analyses are presented.
Metallation reactions. Part 35: A change of the regiochemistry in the metallation of (alkylthio)arenes
Cabiddu, Maria G.,Cabiddu, Salvatore,Cadoni, Enzo,De Montis, Stefania,Fattuoni, Claudia,Melis, Stefana
, p. 3915 - 3920 (2007/10/03)
The metallation reaction of bromo(alkylthio)benzenes is described. The results show the complementarity of these reactions with the metal-hydrogen exchange reaction. In fact, monometallation of bromo(methylthio)benzenes afforded products substituted in para or meta or ortho to the thioethereal function while bimetallation led to αS,para, αS,meta and αS,ortho disubstituted products. Analogously, the monometallation of 4-bromo-(isopropylthio)benzene afforded para-monosubstituted and ortho,para-disubstituted products.
METALATION REACTIONS. IX. DILITHIATION OF AROMATIC THIOETHERS
Cabiddu, Salvatore,Floris, Constantino,Melis, Stefana
, p. 4625 - 4628 (2007/10/02)
Direct dimetalation of aromatic thioethers gives with good yield the dilithiated species 3, 4, 17, 18, 25, 26.The first four species allowed the simultaneous introduction of an electrophile in the thiomethyl group and in the ring, while the last two species undergo disubstitution in the ring.
Photoresponsive Molecular Tweezers. Photoregulated Ion Capture and Release Using Thioindigo Derivatives Having Ethylenedioxy Side Groups
Irie, Masahiro,Kato, Masatoshi
, p. 1024 - 1028 (2007/10/02)
Two trans-cis photoisomerizable thioindigos having CH3OCH2CH2OC(O) or CH3O(CH2CH2O)3C(O) side groups at the 7 and 7' positions, T-1 and T-2, respectively, were synthesized with the aim of controlling the following three functions for achieving fully photoregulated ion transport across a liquid membrane: (1) "all or nothing" type metal ion binding ability, (2) binding ability not only for alkali-metal ions but also for soft metal ions, and (3) photocontrol by visible light.Solvent extraction of metal ions with T-1 revealed that the trans form had no binding ability to any of the metal ions, whereas K+, Rb+, and Na+ were selectively extracted (Na+ + +) by the photogenerated cis form.The cis form, in addition, had high binding ability to Ag+, Hg+, Hg2+, and Cu2+ in comparison to alkali-metal ions.Ion transport experiments across a liquid membrane showed that repeating the cycles of alternate photoirradation of 529- and 488-nm light, which caused isomerization of T-1 from the trans to the cis form (529 nm) and from the cis to the trans (488 nm), resulted in the transportation of Ag+ from aqueous phase I to II through a 1,2-dichloroethane membrane containing T-1.
3-Alkoxy-thianapthene-2-carboxamides
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, (2008/06/13)
The 3-alkoxy-thianaphthene-2-carboxamides of this invention are effective for the treatment of mammals afflicted with emesis. When administered to dogs in dosages of 250 μg/kg, compounds of this invention give 100% protection against vomiting normally induced by subcutaneous administration of apomorphine. The compounds of this invention also favorably modify behavior disturbances in mammals.
