4986-89-4Relevant articles and documents
Facile synthesis of polyester dendrimers as drug delivery carriers
Ma, Xinpeng,Zhou, Zhuxian,Jin, Erlei,Sun, Qihang,Zhang, Bo,Tang, Jianbin,Shen, Youqing
, p. 37 - 42 (2013)
Aliphatic polyester dendrimers are attractive carriers for in vivo delivery of bioactive molecules due to their biocompatibility and biodegradability, but efficient precision synthesis of these dendrimers without tedious purifications remains challenging. Herein, we report an efficient synthesis approach to polyester dendrimers from two AB2-type monomers via combining a click reaction of thiol/acrylate Michael addition with esterification. The reaction solution of each generation contains only the targeted dendrimer macromolecules; thus, the only required separation is simple precipitation. The resulting hydroxyl-terminated fifth-generation dendrimer is thermoresponsive with a LCST of 41 C. The dendrimer could be further pegylated to obtain a water-soluble biocompatible dendrimer capable of encapsulation and controlled release of a hydrophobic anticancer drug, doxorubicin.
Low-viscosity acrylate type compound and compounding application system thereof
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Paragraph 0087-0093, (2019/08/01)
The present invention relates to the field of new materials and fine chemicals, particularly to a class of low-viscosity acrylate type compounds, and a new preparation technology thereof, and applications in alkene-containing unsaturated radiation polymerization systems.
Modified acrylate, preparation method thereof and application of modified acrylate in preparation of conductive adhesive
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Paragraph 0072-0077, (2019/11/28)
The invention discloses modified acrylate, a preparation method thereof and application of modified acrylate in preparation of a conductive adhesive. Hydroxyl groups in a polyol acrylate monomer is converted into alpha-H-containing acetal groups so as to obtain the modified acrylate. The modified acrylate obtained through reduction of hydroxyl groups has low viscosity, and can be effectively usedas a reactive diluent in a photo-cured coating formula, and since the modified acrylate contains the alpha-H-containing acetal groups which can promote photopolymerization activity, the photo-curing activity can be improved, so that photocrosslinking is promoted without addition of a hydrogenation donor assistant, and the problem of oxygen inhibition is avoided. When the modified acrylate is applied to preparation of a photo-cured composition, the prepared photo-cured composition has easy curing and fast surface drying; and the invention also provides a method for preparing the alpha-H-containing acetal groups through a reaction between enol ether and hydroxyl groups of the polyol acrylate monomer, and provides application of the modified acrylate in preparation of the photo-cured composition and the conductive adhesive of the photo-cured composition.
Carbonated polyols and acrylate-based compound thereof
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Paragraph 0091-0093, (2019/08/01)
The invention relates to the field of new materials and fine chemicals, particularly to a class of novel carbonated polyols and (meth)acrylate-based compounds thereof, and a preparation method thereof, and applications in an olefin-containing unsaturated radiation-polymerizable systems.
METHOD FOR PRODUCING (METH)ACRYLATE
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Paragraph 0097-0109, (2018/04/26)
A method for producing a (meth) acrylate comprises transesterification reaction of an alcohol and a monofunctional (meth) acrylate with catalysts in combination being cyclic tertiary amines having an azabicyclo structure and compounds containing zinc, separating a solid that contains the catalysts from a reaction product containing a (meth) acrylate, and producing a (meth) acrylate by transesterification reaction of an alcohol and a monofunctional (meth) acrylate, while using the recovered solid catalyst.
(METH)ACRYLATE MANUFACTURING METHOD
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Paragraph 0103-0104, (2018/05/17)
The present invention provides a (meth)acrylate manufacturing method characterized in that when manufacturing a (meth) acrylate by an ester exchange reaction between an alcohol and a monofunctional (meth)acrylate using catalyst A and catalyst B together, contact treatment of the ester exchange reaction product with adsorbent C is performed. Catalyst A: One or more kinds of compounds selected from a group consisting of cyclic tertiary amines with an azabicyclo structure and salts or complexes thereof, amidine and salts or complexes thereof, compounds with a pyridine ring and salts or complexes thereof, phosphines and salts or complexes thereof, and compounds with a tertiary diamine structure and salts or complexes thereof. Catalyst B: One or more kinds of compounds selected from a group consisting of compounds comprising zinc. Adsorbent C: One or more kinds of compounds selected from a group consisting of oxides and hydroxides comprising at least one of magnesium, aluminum and silicon.
A containing 2, 6 - di-tert-butyl phenol anti-oxidant and its preparation method
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Paragraph 0020; 0087; 0088, (2017/09/26)
The invention reveals a 2,6-di-tert-butylphenol-containing anti-oxidant and a novel preparation method thereof. The method takes titanium, zirconium, hafnium, bismuth, antimony metal complexes as green catalysts, a two-step system is substituted by a series reaction one step method technology, and a high efficiency metal complex catalyst capable of simultaneously catalyzing a direct esterification reaction and a Michael addition reaction is employed to prepare the novel anti-oxidant. The method takes acrylic acid (or acrylic acid ester), pentaerythritol and 2,6-di-tert-butylphenol as main raw materials, under organic solvent or solvent-free condition, the titanium, zirconium, hafnium, bismuth, antimony metal complex green catalysts are reacted to obtain the novel anti-oxidant with high yield. The method has the advantages of low cost, high yield, simple operation and no pollution, and has certain feasibility for realizing industrial production. The preparation method is the green approach with low cost.
MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD
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Paragraph 0087; 0088, (2017/08/07)
[Problem] The purpose of the present invention is to obtain a multifunctional (meth)acrylate with good yield by an ester exchange reaction of a polyhydric alcohol such as pentaerythritol or dipentaerythritol with a monofunctional (meth)acrylate. [Solution] A multifunctional (meth)acrylate manufacturing method characterized in that when manufacturing a multifunctional (meth)acrylate by an ester exchange reaction of a polyhydric alcohol with a monofunctional (meth)acrylate, catalyst (A) and catalyst (B) are used together. Catalyst (A): One or more kinds of compounds selected from a group consisting of cyclic tertiary amines with an azabicyclo structure or salts or complexes thereof, amidines or salts or complexes thereof, and compounds with a pyridine ring or salts or complexes thereof. Catalyst (B): One or more kinds of compounds selected from a group consisting of zinc-containing compounds.
Photo-initiated thiol-ene "click" hydrogels from RAFT-synthesized poly(N-isopropylacrylamide)
Ooi, Huey Wen,Jack, Kevin S.,Whittaker, Andrew K.,Peng, Hui
, p. 4626 - 4636 (2013/10/21)
Despite the efficiency and robustness of the widely used copper-catalyzed 1,3-dipolar cycloaddition reaction, the use of copper as a catalyst is often not attractive, particularly for materials intended for biological systems. The use of photo-initiated thiol-ene as an alternative "click" reaction to synthesize "model networks" is investigated here. Poly(N- isopropylacrylamide) precursors were synthesized by reversible addition fragmentation chain transfer (RAFT) polymerization and were designed to have trithiocarbonate moieties as end groups. This structure design provides opportunity for subsequent end-group modifications in preparation for thiol-ene "click." Two reaction routes have been proposed and studied to yield thiol and ene moieties. The advantages and disadvantages of each reaction path were investigated to propose a simple but efficient route to prepare copper-free "click" hydrogels.
POLYOL DERIVED ANTI-MICROBIAL AGENTS AND COMPOSITIONS
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Page/Page column 13, (2009/12/05)
Anti-microbial compositions are provided which comprise as an antimicrobial agent at least one compound derived from a select polyol containing at least 3 hydroxy groups wherein one or more, and often two or more, of the hydroxyls are derivitized to form certain ether, ester, carbonate or carbamate groups which groups may bear additional functionality. Novel antimicrobial compounds of this class are also provided. The compositions are effective against a variety of pathogens including fungi, Gram positive bacteria and Gram negative bacteria and are expected to have low human toxicity. Applications for the polyglycerol anti-microbial agents and compositions include those involving human and plant contact, such as cosmetics, hair care products, textiles and plant protections, as well as in applications with much less human contact, such as plastics, coatings, wood, paper and other materials of construction.
