122-20-3 Usage
Uses
Used in Cement Industry:
Triisopropanolamine is used as a grinding chemical that reduces agglomeration in the ball milling process and changes the particle distribution of the finished cement. It also acts as an interfacial transition zone (ITZ) to improve the mechanical properties of mortar and concrete, increasing the compressive strength of the cement-fly ash system by accelerating the hydration of both compounds.
Used in Metallurgy:
In the metallurgy industry, Triisopropanolamine is used as antioxidants and coolant to prevent corrosion in metals.
Used in Polyurethane Industry:
Triisopropanolamine has preliminary usage as an agent and catalyst to improve the quality of polyurethane products.
Used in Textile Industry:
In the textile industry, Triisopropanolamine is used as a refining agent and for other dye-specific agent properties.
General Applications:
Triisopropanolamine is used as an emulsifying agent, stabilizer, and chemical intermediate in various industrial applications. It is also used to neutralize acidic components of some herbicides. Major applications include water-based coating applications, agricultural products, antistat agents for polymers, corrosion inhibitors, electrodeposition/electrocoating, lubricants, paper, pigment dispersion, plastics, polyurethane additives, reaction intermediates, rubber curing, surfactants, mineral dispersion, and urethanes.
Air & Water Reactions
Water soluble
Reactivity Profile
Triisopropanolamine neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by combination with strong reducing agents, such as hydrides.
Hazard
Irritant to skin and eyes.
Health Hazard
Irritation of eyes and skin. May cause slight corneal injury or burn. Repeated contact may cause skin burn. Heated vapor may cause moderate respiratory irritation. Low to moderately toxic by oral routes.
Flammability and Explosibility
Nonflammable
Toxicity evaluation
Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine are used as water-soluble emulsifiers and neutralizers in cosmetic products at concentrations up to 1%. In animal studies these ingredients were slightly toxic to practically nontoxic to rats and guinea pigs via acute oral administration. Triisopropanolamine was relatively nontoxic to rats in the two subchronic oral studies. These ingredients were moderate skin irritants for rabbits. All four ingredients, when tested at 100% concentrations, were severe ocular irritants in rabbits. Products containing small amounts (-1%) of Diisopropanolamine or Triisopropanolamine were not ocular irritants in rabbits. The Triisopropanolamine salt was not mutagenic in Aspergillus nidulans. Diisopropanolamine and Isopropanolamine at concentrations of 2% did not induce allergic contact dermatitis or photoallergic dermatitis in humans. Clinical studies on cosmetic products containing no more than 1% Diisopropanolamine or 1.1% Triisopropanolamine were minimal skin irritant and contact sensitizers. It is concluded that Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine are safe as cosmetic ingredients in the present practices of use and concentration. The Isopropanolamines should not be used in products containing N-nitrosating agents.Final Report on the Safety Assessment of Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine
Precautions
Hygroscopic. Store away from oxidizing agents, water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.
References
Pensri Piboonchaisit, et al. Novel Route to Tris(silatranyloxy-i-propyl)amine Directly from Silica and Triisopropanolamine, Part I.ScienceAsia.1999,25113-119.Paul J. Sandberg.; F. Doncaster. On the mechanism of strength enhancement of cement paste and mortar with triisopropanolamine.Cem. Concr. Res.2004,34(6), 973-976.
Check Digit Verification of cas no
The CAS Registry Mumber 122-20-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 122-20:
(5*1)+(4*2)+(3*2)+(2*2)+(1*0)=23
23 % 10 = 3
So 122-20-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H21NO3/c1-7(11)4-10(5-8(2)12)6-9(3)13/h7-9,11-13H,4-6H2,1-3H3/p+1/t7-,8-,9-/m1/s1
122-20-3Relevant articles and documents
ZEOLITE CATALYZED PROCESS FOR THE AMINATION OF PROPYLENE OXIDE
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Page/Page column 20-21, (2021/05/29)
The present invention relates to a process for the conversion of propylene oxide to 1-amino-2- propanol and/or di(2-hydroxypropyl)amine comprising (i) providing a catalyst comprising a zeolitic material comprising YO2 and optionally comprising X2O3 in its framework structure, wherein Y is a tetravalent element and X is a trivalent element, wherein the zeolitic material has a framework-type structure selected from the group consisting of MFI and/or MEL, including MEL/MFI intergrowths; (ii) providing a mixture in the liquid phase comprising propylene oxide and ammonia; (iii) contacting the catalyst provided in (i) with the mixture in the liquid phase provided in (ii) for converting propylene oxide to 1-amino-2-propanol and/or di(2-hydroxypropyl)amine.
Preparation method of isopropanolamine
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Paragraph 0019, (2017/01/23)
A preparation method of isopropanolamine comprising the following steps: 1, weighing isopropanolamine with the mole content of 80% or more and hydrochloric acid according to a ratio of 1:1, wherein the isopropanolamine is MIPA, DIPA and TIPA; 2, adding a calculated amount of hydrochloric acid to a flask with three necks, adding a calculated amount of commercial MIPA or TIPA in batches under stirring until the pH value is 2 at below 40DEG C, precipitating crystals, continuously stirring for cooling to 0DEG C, filtering to respectively obtain MIPA.HCl or TIPA.HCl, mixing the above obtained two mother liquors, and carrying out reduced pressure dewatering to obtain DIPA.HCl; or adding the calculated amount of hydrochloric acid to the flask with three necks, adding a calculated amount of commercial DIPA in batches under stirring until the pH value is 2 at below 40DEG C, cooling to 0DEG C, filtering to obtain a filter cake to be processed, and carrying out reduced pressure distillation under 100mmHg on the obtained filtrate until no precipitate precipitates to obtain DIPA.HCl; and 3, respectively carrying out a free reaction on the MIPA.HCl, DIPA.HCl and TIPA.HCl and an equivalent amount of a methanol solution of sodium methoxide, filtering to remove salt, and carrying out reduced pressure distillation on the above obtained methanol recovered solution to respectively obtain high-quality MIPA, DIPA and TIPA with the content of 97-99%. The obtained isopropanolamine can completely substitute imported products, meets domestic needs, and has substantial benefits.
PROCESS OF MAKING BETA-HYDROXYAMINO COMPOUNDS
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Page/Page column 10, (2013/02/27)
The present application relates to molecules comprising one or more beta-hydroxyamine moieties, for example, aminosilicones and compositions such as consumer products comprising such molecules, as well as processes for making and using such molecules and such compositions. The aforementioned process is safer, more efficient and thus more economical. Thus, the aforementioned moleculers may be more widely used.
Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
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, (2008/06/13)
Biodegradible polymers are provided which may contain a biologically active substance, e.g. a drug such as insulin, which is released over a period of time as the polymer erodes when in contact with a body fluid. The polymer contains an amine functionality whereby it erodes faster at low acid pH's than at higher acid pH's. As an example, the polymer may contain insulin and may contain or may have an encapsulating hydrogel containing glucose oxidase. As the blood sugar level of a diabetic person rises, e.g., afte a meal, glucose diffuses into the polymer or hydrogel and is converted to gluconic acid which lowers the pH, and accelerates erosion and the release of insulin.
Organic quaternary ammonium compounds and process for the preparation thereof
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, (2008/06/13)
Quaternary ammonium compounds having the general formula: STR1 in which, R1 is an alkyl or aryl group, unsubstituted or substituted by at least two ester groups; R2, R3 and R4 are alkyl, aryl, aryl alkyl or alkyl aryl groups substituted by ester groups comprising no more than 10 carbon atoms; m, r and n are whole numbers; A r- is an anion such that m×r=n. The compounds are obtained by treatment of a tert.alcohol-amine with an alkylating or arylating agent and an acylating agent. They may be used as activators of persalts in wash compositions.
