Welcome to LookChem.com Sign In|Join Free

Cas Database

41979-39-9

41979-39-9

Identification

  • Product Name:4-Piperidinone,hydrochloride (1:1)

  • CAS Number: 41979-39-9

  • EINECS:255-602-8

  • Molecular Weight:135.594

  • Molecular Formula: C5H10ClNO

  • HS Code:2933399090

  • Mol File:41979-39-9.mol

Synonyms:4-Piperidinone,hydrochloride (9CI);4-Oxopiperidine hydrochloride;4-Piperidone hydrochloride;Piperidin-4-one monohydrate hydrochloride;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Piperidin-4-one hydrochloride 97%
  • Packaging:25 g
  • Price:$ 36
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Piperidin-4-one hydrochloride 97%
  • Packaging:100 g
  • Price:$ 96
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Medical Isotopes, Inc.
  • Product Description:piperidin-4-one 97%
  • Packaging:1 g
  • Price:$ 680
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Piperidin-4-one hydrochloride 97%
  • Packaging:100g
  • Price:$ 237
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Piperidin-4-one hydrochloride 97%
  • Packaging:25g
  • Price:$ 91
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Piperidin-4-one hydrochloride 97%
  • Packaging:5g
  • Price:$ 28
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Chemenu
  • Product Description:Piperidin-4-onehydrochloride 97%
  • Packaging:1000g
  • Price:$ 499
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Cayman Chemical
  • Product Description:4-Piperidone (hydrochloride) ≥95%
  • Packaging:50mg
  • Price:$ 68
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Cayman Chemical
  • Product Description:4-Piperidone (hydrochloride) ≥95%
  • Packaging:10mg
  • Price:$ 15
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Apolloscientific
  • Product Description:Piperidin-4-onehydrochloride 95%
  • Packaging:25g
  • Price:$ 32
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 12 Articles be found

Cation-Cation Pairing by Ni-Ci-H?O Hydrogen Bonds

Gamrad, Waltraud,Dreier, Angelika,Goddard, Richard,P?rschke, Klaus-Richard

, p. 4482 - 4487 (2015)

The pairing of ions of opposite charge is a fundamental principle in chemistry, and is widely applied in synthesis and catalysis. In contrast, cation-cation association remains an elusive concept, lacking in supporting experimental evidence. While studying the structure and properties of 4-oxopiperidinium salts [OC5H8NH2]X for a series of anions X- of decreasing basicity, we observed a gradual self-association of the cations, concluding in the formation of an isolated dicationic pair. In 4-oxopiperidinium bis(trifluoromethylsulfonyl)amide, the cations are linked by N-H?O=C hydrogen bonds to form chains, flanked by hydrogen bonds to the anions. In the tetra(perfluoro-tert-butoxy)aluminate salt, the anions are fully separated from the cations, and the cations associate pairwise by N-C-H?O=C hydrogen bonds. The compounds represent the first genuine examples of self-association of simple organic cations based merely on hydrogen bonding as evidenced by X-ray structure analysis, and provide a paradigm for an extension of this class of compounds.

QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF

-

Paragraph 00633-00634, (2020/10/09)

Compounds and methods for their preparation and use as therapeutic or prophylactic agents, fo example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase- 1 (ENPP1).

Synthesis and antibacterial evaluation of novel oxazolidinone derivatives containing a piperidinyl moiety

Hou, Yunlei,Dong, Yuhong,Ye, Tianyu,Jiang, Jia,Ding, Liang,Qin, Mingze,Ding, Xiudong,Zhao, Yanfang

, (2019/11/11)

In this article, a series of novel oxazolidinone derivatives containing a piperidinyl moiety was designed and synthesized. Their antibacterial activities were measured against S. aureus, MRSA, MSSA, LREF and VRE by MIC assay. Most of them exhibited potent activity against Gram-positive pathogens comparable to linezolid. Among them, compound 9h exhibited comparable activity with linezolid against human MAO-A for safety evaluation and showed moderate metabolism in human liver microsome. The most promising compound 9h, which showed remarkable antibacterial activity against S. aureus, MRSA, MSSA, LREF and VRE pathogens with MIC value of 0.25–1 μg/mL, was an interesting candidate for further investigation.

LSD1 Inhibitors

-

Paragraph 0435; 0436, (2017/07/14)

The present invention relates to compounds that inhibit LSD1 activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

PHENYL AMINO PYRIMIDINE BICYCLIC COMPOUNDS AND USES THEREOF

-

Page/Page column 37, (2014/01/17)

The present invention relates to phenyl amino pyrimidine bicyclic compounds formula (I) which are inhibitors of protein kinases including JAK kinases. In particular the compounds are active against JAK1, JAK2, JAK3 and TYK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Process route upstream and downstream products

Process route

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; In methanol; at 0 - 20 ℃;
100%
With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃; for 2h;
99%
With hydrogenchloride; In 1,4-dioxane; at 15 ℃; for 12h;
97%
With hydrogenchloride; In 1,4-dioxane; at 0 ℃; for 4h;
With hydrogenchloride; In ethyl acetate; at 20 ℃; for 2h;
With hydrogenchloride; In methanol; dichloromethane; at 20 ℃;
With hydrogenchloride; at 25 ℃; for 5h;
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; hydrogen; palladium dihydroxide; In ethanol; at 20 ℃; for 24h; under 3102.89 Torr;
97%
3-[3-(4-hydroxypiperidinylazo)phenoxy]propyloxymethylpolystyrene

3-[3-(4-hydroxypiperidinylazo)phenoxy]propyloxymethylpolystyrene

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
3-[3-(4-hydroxypiperidinylazo)phenoxy]propyloxymethylpolystyrene; With pyridine; Dess-Martin periodane; In dichloromethane; at 20 ℃; for 72h;
With trifluoroacetic acid; In dichloromethane; at 0 ℃;
With hydrogenchloride; In dichloromethane; Further stages.;
62%
4-Oxo-piperidine-3-carboximidic acid methyl ester; hydrochloride

4-Oxo-piperidine-3-carboximidic acid methyl ester; hydrochloride

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; for 0.5h; Heating;
50%
piperidine-4,4-diol hydrochloride
40064-34-4

piperidine-4,4-diol hydrochloride

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
With thionyl chloride;
4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

Conditions
Conditions Yield
4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

acetic acid
64-19-7,77671-22-8

acetic acid

2-Fluorobenzaldehyde
446-52-6

2-Fluorobenzaldehyde

3,5-bis-(2-fluorobenzylidene)-4-piperidone acetic acid
342808-41-7

3,5-bis-(2-fluorobenzylidene)-4-piperidone acetic acid

Conditions
Conditions Yield
at 20 ℃; for 48h;
94%
4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

cyclohexylmethyl chlorocarbonate
6099-86-1

cyclohexylmethyl chlorocarbonate

benzyl 4-oxo-1-piperidinecarboxylate
19099-93-5

benzyl 4-oxo-1-piperidinecarboxylate

Conditions
Conditions Yield
With potassium carbonate; In tetrahydrofuran; water; at -5 - 20 ℃; for 2.33333h;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

benzyl 4-oxo-1-piperidinecarboxylate
19099-93-5

benzyl 4-oxo-1-piperidinecarboxylate

Conditions
Conditions Yield
With potassium carbonate; In dichloromethane; water; at 20 ℃; for 2h;
98.6%
4-piperidone hydrochloride
41979-39-9

4-piperidone hydrochloride

benzyl chloroformate
501-53-1,94274-21-2

benzyl chloroformate

piperidin-2-one
675-20-7

piperidin-2-one

benzyl 4-oxo-1-piperidinecarboxylate
19099-93-5

benzyl 4-oxo-1-piperidinecarboxylate

Conditions
Conditions Yield
With sodium hydroxide; In tetrahydrofuran; water;
With sodium hydroxide; In tetrahydrofuran; water;

Global suppliers and manufacturers

Global( 64) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
  • COLORCOM LTD.
  • Business Type:Manufacturers
  • Contact Tel:+86-571-89007001
  • Emails:medkem@medkem.cn
  • Main Products:1
  • Country:China (Mainland)
  • Shaanxi BLOOM TECH Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-29-86470566
  • Emails:sales@bloomtechz.com
  • Main Products:79
  • Country:China (Mainland)
  • Shanghai Upbio Tech Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-21-52196435
  • Emails:emmahu@up-bio.com
  • Main Products:88
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 41979-39-9
Post Buying Request Now
close
Remarks: The blank with*must be completed