917-61-3 Usage
Description
Sodium cyanate is the sodium salt of cyanic acid, a versatile chemical compound widely used in the chemical industry and medicine. It is recognized for its nucleophilic properties, which play a significant role in the stereospecificity of certain reactions, such as the production of chiral oxazolidone. Sodium cyanate also serves as a reagent in the synthesis of asymmetrical ureas, which exhibit a range of biological activities, particularly in aryl isocyanate intermediates.
Uses
Used in Biological Studies:
Sodium cyanate is utilized as a tumor cell proliferation and metabolism inhibitor, playing a crucial role in biological research and potentially offering counterbalancing effects against carcinogenic processes in the human body.
Used in Organic Synthesis:
In the field of organic synthesis, sodium cyanate acts as an intermediate for the production of various compounds, including dye-stuffs, bulk drugs, and heat treatment salts for metals.
Used in Pharmaceutical Industry:
Sodium cyanate is employed as an intermediate in the manufacture of medicinals, contributing to the development of pharmaceuticals with potential applications in treating conditions such as sickle cell anemia and obesity.
Used in Agriculture:
Sodium cyanate is used in the production of fungicides and herbicides, helping to protect crops and maintain agricultural productivity.
Used in Photography:
In the photography industry, sodium cyanate serves as a photographic initiator, playing a vital role in the development of photographic films and papers.
References
https://en.wikipedia.org/wiki/Sodium_cyanate
http://www.recentlab.com/sodiumcyanate.htm
http://www.jfine.co.jp/eng/chemicals/use/cyanate/index.html
Flammability and Explosibility
Nonflammable
Safety Profile
Poison by ingestion,
intraperitoneal, and intramuscular routes.
Human systemic effects by ingestion: weight
loss, changes in the visual field, and other
eye effects. See also CYANATES. When
heated to decomposition it emits very toxic
fumes of CNand Na2O.
Purification Methods
It forms colourless needles from EtOH. Its solubility in EtOH is 0.22g/100g at 0oC. It is soluble in H2O but can be recrystallised from small volumes of it.
Check Digit Verification of cas no
The CAS Registry Mumber 917-61-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,1 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 917-61:
(5*9)+(4*1)+(3*7)+(2*6)+(1*1)=83
83 % 10 = 3
So 917-61-3 is a valid CAS Registry Number.
InChI:InChI=1/CNO.Na/c2-1-3;/q-1;+1
917-61-3Relevant articles and documents
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Donald
, p. 2255 (1925)
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CROSS-LINKED COMPOSITIONS
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, (2011/05/16)
Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and preferably prepared in a non-phosphate buffer solvent. Optionally and preferably, the cross-linkable protein includes gelatin and any gelatin variant or variant protein as described herein. Optionally and preferably, the non-toxic material comprises transglutaminase (TG), which may optionally comprise any type of calcium dependent or independent transglutaminase, which may for example optionally be a microbial transglutaminase (mTG).
Kinetics and mechanism of alkaline hydrolysis of urea and sodium cyanate
Khan, Zaheer,Rafiquee,Kabir-ud-din,Arif Niaz,Aziz Khan
, p. 1116 - 1119 (2007/10/03)
The kinetics of hydrolysis of urea has been studied in 0.5 to 3.0 mol dm-3 sodium hydroxide solution at different temperatures. Urea hydrolysis follows an irreversible first order consecutive reaction path: equation presented The variation of Klobs with [alkali] is linear at [OH-] = 5.0 to 1.5 mol dm-3, thereafter a sharp increase in the reaction rate is observed for first step hydrolysis of urea. The second step rate constant (K2obs) is found to be independent of [alkali]. Hydrolysis of urea in alkaline medium follows an elemination-addition mechanism. The reaction does not proceed through the formation and decomposition of tetrahedral intermediate. Sodium cyanate hydrolysis obeys an irreversible pseudo-first order kinetics. [OH-] has no significant effect on the rate constants. The following rate equations have been derived for the two step hydrolysis of urea. Klobs = K0 + K1[OH-](K4 + K3[OH-])/K-1 + K4 + K3[OH-] K2obs = K2Kh On the basis of observed data, probable mechanisms have been proposed.