An osmium-DNA interstrand complex: Application to facile DNA methylation analysis

DOI: 10.1021/ja076140r

Source and publish data:

Journal of the American Chemical Society p. 14511 - 14517 (2007)

Update date:2022-08-03

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Authors:

Tanaka, Kazuo

Tainaka, Kazuki

Umemoto, Tadashi

Nomura, Akiko

Okamoto, Akimitsu

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Article abstract of DOI:10.1021/ja076140r

Nucleic acids often acquire new functions by forming a variety of complexes with metal ions. Osmium, in an oxidized state, also reacts with C5-methylated pyrimidines. However, control of the sequence specificity of osmium complexation with DNA is still im

Full text of DOI:10.1021/ja076140r

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