THEXYLDIMETHYLSILYL CHLORIDE, AN EASILY ACCESSIBLE REAGENT FOR THE PROTECTION OF ALCOHOLS

DOI: 10.1016/S0040-4039(01)80874-1

Source and publish data:

Tetrahedron Letters p. 5515 - 5518 (1985)

Update date:2022-08-03

Topics:

Authors:

Wetter, Hansjuerg

Oertle, Konrad

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Article abstract of DOI:10.1016/S0040-4039(01)80874-1

The silylation of alcohols, amines, amides, mercaptans and acids with the readily available thexyldimethylsilyl chloride (TDS-CI) is described.The stabilities of the silyl ethers are examined using different cleavage conditions and compared in part with the stabilities of the corresponding tert-butyldimethylsilyl derivatives.

Full text of DOI:10.1016/S0040-4039(01)80874-1

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