Efficient palladium-catalyzed direct arylation of azines and diazines using ligand-free conditions

Article abstract of DOI:10.1016/j.tet.2009.02.025

The use of the palladium-catalyzed direct arylation was successfully tested on different electron-deficient heterocycles. The results demonstrate the effectiveness of the method based on the intramolecular coupling reaction providing polyazacyclic systems