Synthesis and Antitumor Activity of Analogues of Ifosfamide Modified in the N-(2-Chloroethyl) Group

DOI: 10.1021/jm00396a036

Source and publish data:

Journal of Medicinal Chemistry p. 226 - 230 (1988)

Update date:2022-08-02

Topics:

Authors:

Misiura, Konrad

Kinas, Ryszard W.

Stec, Wojciech J.

Kusnierczyk, Halina

Radzikowski, Czeslaw

Sonoda, Akio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00396a036

A series of 3-(2-chloroethyl)-N-(2-X-ethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxides with various X substituents have been prepared by cyclization of racemic ifosfamide or its enantiomers with sodium hydride and subsequent treatment of intermed

Full text of DOI:10.1021/jm00396a036

Products guided by the article

Product name:2H-1,3,2-Oxazaphosphorin-2-amine,N-(2-bromoethyl)-3-(2-chloroethyl)tetrahydro-, 2-oxide, (2S)-

Cas No:104149-15-7

R&D Labs maybe for 104149-15-7

GN chemicals co.,ltd

Contact:86 311 85902108 / 85902109

Address:room 1001-1005 ,huanghe Road ,shijiazhuang ,China
qingdao goldenchem imp and exp co.,ltd.

Contact:532-55579246

Address:no.62 ,haier road laoshan distirct
JiYi Chemical (Beijing) Co., Ltd.

Contact:+86-10-89385733

Address:Shilou Town of Fangshan District， Beijing
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China

Relevant to this article

Iron(II) bromide-catalyzed synthesis of benzimidazoles from aryl azides

Doi:10.1021/ol801227f
(2008)
Doi:10.1039/jr9520004346
(1952)
Doi:10.1007/BF00480954
()
Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2- pyrimidinyl]amino]-2-methyl-benzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor

Doi:10.1021/jm800566m
(2008)
Dehydrogenative cyclocondensation of aldehydes, alkynes, and dialkylsilanes

Doi:10.1021/ja803774s
(2008)
Synthesis of fused 1-sila-, 1-germa-, and 1-selenacyclohepta-2,4,6-trienes

Doi:10.1021/om8003114
(2008)

Article Doi