A facile preparation of 4-thiazolone derivatives from thioamides and various haloacyl halides in a biphase system

DOI: 10.1248/cpb.33.3479

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3479 - 3483 (1985)

Update date:2022-08-03

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Authors:

Okawara Okawara

Kashihara

Furukawa

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Article abstract of DOI:10.1248/cpb.33.3479

The reaction of thioamides (1) with various haloacyl halides (2, 7, 11, 14, 17, and 19) was carried out in sat. NaHCO₃-CH₂Cl₂ and 5% NaOH-CH₂C1₂ to give several kinds of 4-thiazolones (3-5, 10, 12 and

Full text of DOI:10.1248/cpb.33.3479

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