2-Phenylindoles. Effect of N-Benzylation on Estrogen Receptor Affinity, Estrogenic Properties, and Mammary Tumor Inhibiting Activity

DOI: 10.1021/jm00384a022

Source and publish data:

Journal of Medicinal Chemistry p. 131 - 136 (1987)

Update date:2022-08-04

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Authors:

Angerer, Erwin von

Strohmeier, Josef

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Article abstract of DOI:10.1021/jm00384a022

Hydroxy-2-phenylindoles carrying substituted benzyl groups and similar substituents at the nitrogen were synthesized and tested for their ability to displace estradiol from its receptor. All of the derivatives tested exhibited high binding affinities for

Full text of DOI:10.1021/jm00384a022

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