Bioorganic and Medicinal Chemistry Letters p. 4438 - 4441 (2008)
Update date:2022-09-26
Topics:
Purandare, Ashok V.
Chen, Zhong
Huynh, Tram
Pang, Suhong
Geng, Jieping
Vaccaro, Wayne
Poss, Michael A.
Oconnell, Jonathan
Nowak, Kimberly
Jayaraman, Lata
This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.
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