Chemo-enzymatic syntheses of drimane-type sesquiterpenes and the fundamental core of hongoquercin meroterpenoid by recombinant squalene-hopene cyclase

DOI: 10.1039/c1ob06419c

Source and publish data:

Organic and Biomolecular Chemistry p. 440 - 446 (2012)

Update date:2022-09-26

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Authors:

Yonemura, Yukie

Ohyama, Takuro

Hoshino, Tsutomu

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Article abstract of DOI:10.1039/c1ob06419c

Squalene-hopene cyclase (SHC) converts squalene (C₃₀) into pentacyclic triterpenes of hopene and hopanol. A linear sesquiterpene, (6E,10E)-2,6,10-trimethyldodeca-2,6,10-triene, underwent cyclization catalyzed by SHC, affording the following six

Full text of DOI:10.1039/c1ob06419c

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