
Journal of Medicinal Chemistry p. 3254 - 3263 (1992)
Update date:2022-08-05
Topics:
Rovnyak, George C.
Atwal, Karnail S.
Hedberg, Anders
Kimball, David S.
Moreland, Suzanne
et al.
We have examined a series of novel dihydropyrimidine calcium channel blockers that contain a basic group attached to either C5 or N3 of the heterocyclic ring.Structure-activity studies show that a 1-(phenylmethyl)-4-piperidinyl carbamate moiety at N3 and
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(1960)