Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives

DOI: 10.1016/S0960-894X(99)00520-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3057 - 3060 (1999)

Update date:2022-08-04

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Authors:

Ohyama, Masayoshi

Tanaka, Toshiyuki

Ito, Tetsuro

Iinuma, Munekazu

Bastow, Kenneth F.

Lee, Kuo-Hsiung

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Article abstract of DOI:10.1016/S0960-894X(99)00520-X

Eleven resveratrol oligomers and six acetylated derivatives were evaluated for in vitro cytotoxicity against a panel of human tumor cell lines. The acetate of (-)-ampelopsin A (12) showed potent and selective cytotoxic activity with ED₅₀ values

Full text of DOI:10.1016/S0960-894X(99)00520-X

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