Chemistry of Natural Compounds p. 435 - 438 (1986)
Update date:2022-08-03
Topics:
D'yakonov, A. L.
Telezhenetskaya, M. V.
Yunusov, L. Yu.
Monosubstituted 5-, 6-, and 8-methoxy-3,4-dihydro-2,3-pentamethylenequinazolones (1-3) have been synthesized by the condensation of monosubstituted methoxyanthranilic acids with caprolactam.Demethylation with hydrobromic acid gave the corresponding hydroxy compounds <4-6>.When the 6- and 8-methoxy- and 6- and 8-hydroxy-3,4-dihydro-2,3-pentamethylenequinazolones (2, 3, 5, and 6) were reduced with zinc in hydrochloric acid, the corresponding quinazoline derivatives (7-10) were obtained.The melting points of the bases and their hydrochlorides are given.Some features of their UV, mass, and PMR spectra are reported.
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