Journal of Organic Chemistry p. 3319 - 3322 (1987)
Update date:2022-08-02
Topics:
Hegedus, Louis S.
Toro, Jose L.
Miles, William H.
Harrington, Peter J.
(+/-)-Aurantioclavine (9) was synthesized in overall 23percent yield and 13 steps from comercially available starting materials.The synthesis involved palladium(II)-catalyzed indole ring formation, nickel(0)/zirconium(IV)-assisted introduction of one side chain, palladium(0)-catalyzed introduction of the other side chain, acid-catalyzed cyclization to form the seven-membered ring, and photolytic reductive detosylation to produce 9.
View MoreSHANGHAI T&W PHARMACEUTICAL CO., LTD.
website:http://www.trustwe.com
Contact:+86-21-61551413
Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong
Contact:86-511-85210668 0511-85210668, 85210818, 85210898
Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Shandong Topscience Biotech Co., Ltd.
Contact:0633-2619278
Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China
Shanghai Dianyang Industry Co.,ltd
Contact:+86 21 6492 4669
Address:Chejing RD, Songjiang District, Shanghai, China
Melone Pharmaceutical Co., ltd
Contact:+86-411 82593920, 82593631
Address:No 232, JInma Roda, Development Zone, Dalian, China
Doi:10.1021/ja01558a048
(1957)Doi:10.1039/c2ce06754d
(2012)Doi:10.1021/jm00392a022
(1987)Doi:10.1246/bcsj.59.3013
(1986)Doi:10.1021/acs.jmedchem.7b00210
(2017)Doi:10.1021/ol802295b
(2008)
