Imine allylation using 2-alkoxycarbonyl allylboronates as an expedient three-component reaction to polysubstituted α-exo-methylene-γ-lactams

DOI: 10.1016/j.tetlet.2008.09.112

Source and publish data:

Tetrahedron Letters p. 6995 - 6998 (2008)

Update date:2022-07-31

Topics:

Authors:

Elford, Tim G.

Hall, Dennis G.

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Article abstract of DOI:10.1016/j.tetlet.2008.09.112

α-exo-Methylene-γ-lactams are key structural units in a wide variety of biologically active natural products. A concise route to the formation of polysubstituted α-exo-methylene-γ-lactams is described. In this three-component reaction, an imine is formed

Full text of DOI:10.1016/j.tetlet.2008.09.112

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