
Journal of Organic Chemistry p. 5487 - 5489 (1987)
Update date:2022-08-16
Topics: Termination Manganese(III) Polycyclization
Snider, Barry B.
Dombroski, Mark A.
Oxidative free radical cyclization of β-keto esters such as 1a with Mn(OAc)3*2H2O and Cu(OAc)2*H2O leads to bicyclic products such as 6a in excellent yield.The key steps are oxidation of 1a to 2a by Mn(OAc)3*2H2O, two successive free radical cyclizations
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