Journal of Medicinal Chemistry p. 250 - 254 (1988)
Update date:2022-07-29
Topics: NMR spectra Mass spectra TLC analysis Nucleoside Enzyme inhibition Chemotherapy
Elliott, Robert D.
Thomas, H. Jeanette
Shaddix, Sue C
Adamson, Doris J.
Brokman, R. Wallace
et al.
Several nitrosoureido nucleosides (3a, 3b, 5a, 7a, 7c, and 10a) designed as inhibitors of enzyme that metabolize pyrimidine nucleotides have been prepared and their chemical and biological properties studied.The methylnitrosoureas 3a and 3b were not signi
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