Tetrahedron Letters p. 7955 - 7958 (1996)
Update date:2022-08-04
Topics:
Bertram, Gunda
Scherer, Angela
Steglich, Wolfgang
Weber, Wolfgang
Anke, Timm
The potent antifungal and cytostatic antibiotic strobilurin E (1) has been obtained in 6 steps from 3,4-dihydroxybenzaldehyde (3) and the bromoketone 2. The strobilurin side chain was elaborated by three consecutive Wittig reactions and a photochemical double bond isomerisation.
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