Design, synthesis and evaluation of synthetic receptors for the recognition of aspartate pairs in an α-helical confirmation

Article abstract of DOI:10.1016/S0968-0896(97)00086-2

The specific targeting of protein surface functional groups remains a largely unexplored aspect in molecular recognition. In this study, a series of zwitterionic, 16-mer peptides serve as models for the recognition of carboxylate pairs in proteins. A rece