Methyl (E)-4-chloro-3-methoxy-2-butenoate: An extremely versatile four carbon building block

DOI: 10.1055/s-1992-26120

Source and publish data:

Synthesis p. 391 - 394 (1992)

Update date:2022-09-26

Topics:

Authors:

Duc Duc

McGarrity

Meul Meul

Warm Warm

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Article abstract of DOI:10.1055/s-1992-26120

Methyl (E)-4-chloro-3-methoxy-2-butenoate (3a) is inexpensively prepared from methyl 4-chloroacetoacetate using thionyl chloride and methanol on an industrial scale. Many nucleophilic substitution reactions of chloride, which are impossible with the unpro

Full text of DOI:10.1055/s-1992-26120

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