Homoallylic amines related to zimeldine. A comparative study on neuronal serotonin and norepinephrine reuptake based on conformational analysis

DOI: 10.1021/jm00400a005

Source and publish data:

Journal of Medicinal Chemistry p. 913 - 919 (1988)

Update date:2022-07-30

Topics: Conformational Analysis Comparative study

Authors:

Hogberg Hogberg

Ross Ross

Strom Strom

Grunewald

Creese Creese

Bunce Bunce

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Article abstract of DOI:10.1021/jm00400a005

A number of tertiary and secondary homoallylic amines (i.e. (Z)- and (E)-4-(4-bromophenyl)-4-(3-pyridyl)-3-buten-1-ylamines, were synthesized in diastereomerically pure forms. The compounds were evaluated as neuronal norepinephrine (NE) and serotonin (5-H

Full text of DOI:10.1021/jm00400a005

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