Tetrahedron Letters p. 1997 - 2000 (1987)
Update date:2022-08-04
Topics:
Ardisson, J.
Ferezou, J.P.
Julia, M.
Lenglet, L.
Pancrazi, A.
A diastereocontrolled synthesis of the spiroketal sub-unit of 22,23-dihydroavermectin B1b has been developed using a formal double condensation at both ends of pentane 2,4-dione 3 with intermediate formation of the ketal 5.
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Doi:10.3987/COM-08-11432
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(2009)
