Organic Letters p. 1995 - 1997 (2009)
Update date:2022-07-29
Topics:
Tone, Hitoshi
Buchotte, Marie
Mordant, Celine
Guittet, Eric
Ayad, Tahar
Ratovelomanana-Vidal, Virginie
The asymmetric total synthesis of the originally proposed structure of gymnangiamide, a cytotoxic pentapeptide isolated from the marine hydroid Gymnangium regae Jaderholm, has been achieved. Key to the synthesis was the use of asymmetric hydrogenation of
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