Tetrahedron p. 1283 - 1292 (1989)
Update date:2022-08-04
Topics:
Galluci, Judith C.
Ha, Deok-Chan
Hart, David J.
The dianion of (S)-ethyl β-hydroxybutyrate (1) was treated with N-trimethylsilyl imine 2 to afford β-lactam 4.The same dianion reacted with N-aryl imine 10 to give β-lactams 11, 12, and 13.A three-step sequence was used to convert 4 into the β-lactam-pyra
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