Journal of Organic Chemistry p. 109 - 115 (1989)
Update date:2022-07-29
Topics:
Kemp, D.S.
Carter, Jeffery S.
A practical synthesis of the conformationally restricted amino acid analogue methyl N-<4-<6-(benzyloxycarbonyl)-3-cyano-6-azabicyclo<3.2.1>oct-2-enyl>>-L-alaninate (12ab) from 4-hydroxyproline is described.Blocking and Barton cyanoethylation generates N-(
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