Tetrahedron Letters p. 3111 - 3114 (1988)
Update date:2022-08-04
Topics:
Ranganathan, S.
Ranganathan, D.
Singh, W. P.
The chain shortened analog of lysine, H2NCH2CH2CH(NHZ)COOR, generated from N-protected glutamine esters, undergoes spontaneous cyclization.The results show that amino acids having H2NCH2CH2 - side chains cannot be supported on tRNA and provides a rationale for keeping the amino group of lysine by as many as four methylenes away from the peptide backbone.In sharp contrast, in the peptide environment, H2NCH2CH2CH(NHZ)CONHCH(X)COOMe, this unit is stable, thus demonstrating that if they are post translationally created, can be present as viable side chains in proteins.
View MoreHangzhou yi lu biont technology Co., LTD
Contact:+86-571-88152630
Address:Hangzhoushi HuafengRoad Yicheng3Building1001room.
Contact:13357117572
Address:No.149 Shiji dadao Road.
Daqing New Century Fine Chemical Co., Ltd.(expird)
Contact:010-57126694
Address:No.39, jinxing cun, honggang district
Shanghai Hanhong Scientific Co.,Ltd.
website:http://www.chemvia.com
Contact:+86-21-64541543,54280654,13918533501
Address:Jiachuan Road 245
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
website:http://www.shydtec.com
Contact:86-21-57721279
Address:Science and Technology Park, Songjiang District, Shanghai, China
Doi:10.1016/0301-0104(93)80244-4
(1993)Doi:10.1016/j.ejmech.2014.02.032
(2014)Doi:10.1016/0040-4020(96)00951-9
(1996)Doi:10.1021/jo00101a051
(1994)Doi:10.1016/S0040-4039(00)73121-2
(1994)Doi:10.1016/S0040-4020(01)89595-8
(1994)
