
Tetrahedron Letters p. 7973 - 7974 (1993)
Update date:2022-08-02
Topics:
Garcia, Mariano
Del Campo, Carmen
Sinisterra, Jose V.
Llama, Emilio F.
The addition of dihalocarbenes to arylmethylketones in the presence of low-valent titanium yields 2-aryl propionic acids in acceptable yield by one pot reaction. The reaction conditions were optimized. The TiCl4/LiAlH4 ratio is one variable that controls the selectivity of the process.
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