Journal of the Brazilian Chemical Society p. 546 - 550 (2016)
Update date:2022-07-30
Topics:
Mansouri, Rachida
Aouf, Zineb
Lakrout, Salah
Berredjem, Malika
Aouf, Nour-Eddine
A simple, eco-sustainable method for the N-(9-fluorenylmethoxycarbonyl) (N-Fmoc) protection of various structurally amines under ultrasonic irradiation is reported. The corresponding N-Fmoc derivatives were obtained in good to excellent yields within short reaction time. The reaction proceeds without the formation of any side product. Mildness, efficiency and easier work are the main advantages of this new protocol.
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(2016)