Bioorganic and Medicinal Chemistry Letters p. 5962 - 5964 (2009)
Update date:2022-09-26
Topics:
Darque, Albert
Dumetre, Aurelien
Hutter, Sebastien
Casano, Gilles
Robin, Maxime
Pannecouque, Christophe
Azas, Nadine
We have synthesized quinolinones with potential antiparasitic and anti-HIV activities by an original two-step method involving microwave irradiation and have evaluated their activities against Plasmodium falciparum, Leishmania donovani, Trichomonas vaginalis, and HIV. None of the tested compounds had been previously described using this method of synthesis. One of the compounds had interesting antiparasitic and anti-HIV activity, which could be improved by substitution with different radicals.
View MoreSichuan Sangao Biochemical Co., Ltd
Contact:+86-28-84874233
Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
Contact:+49-9398-993127
Address:Untertorstr. 27
Hubei Lingsheng Pharmaceuticals Co., Ltd.
Contact:+86-0710-3538058
Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Anqing World Chemical Co., Ltd.
Contact:+86-556-5800026
Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
Contact:+86-21-61318535
Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
Doi:10.1016/j.poly.2011.03.028
(2011)Doi:10.1021/ol902301h
(2009)Doi:10.1039/b914030a
(2009)Doi:10.1039/b912782h
(2009)Doi:10.2174/157017809788681275
(2009)Doi:10.1021/ol902354f
(2009)
