Probes for Narcotic Receptor Mediated Phenomena. 15. (3S,4S)-(+)-trans-3-Methylfentanyl Isothiocyanate, a Potent Site-Directed Acylating Agent for the δ Opioid Receptors in Vitro

DOI: 10.1021/jm00126a040

Source and publish data:

Journal of Medicinal Chemistry p. 1392 - 1398 (1989)

Update date:2022-08-02

Topics:

Authors:

Kim, Chong-Ho

Rothman, Richard B.

Jacobson, Arthur E.

Mattson, Mariena V.

Bykov, Victor

et al. et al.

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Article abstract of DOI:10.1021/jm00126a040

Recently we reported the synthesis of the first enantiomeric pair of irreversible opioid ligands <(3S,4R)-(-)- and (3R,4S-(+)-cis-4, SUPERFIT> and specific interaction of the latter with the δ receptor.Here we report another enantiomeric pair of irreversi

Full text of DOI:10.1021/jm00126a040

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