HIGHLY REGIOSELECTIVE RING-OPENING OF α-SUBSTITUTED CYCLIC ACID ANHYDRIDES CATALYZED BY LIPASE

DOI: 10.1016/S0040-4039(00)99517-0

Source and publish data:

Tetrahedron Letters p. 1555 - 1556 (1989)

Update date:2022-08-05

Topics:

Authors:

Hiratake, Jun

Yamamoto, Kazuyoshi

Yamamoto, Yukio

Oda, Jun'ichi

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Article abstract of DOI:10.1016/S0040-4039(00)99517-0

Lipase Amano P irreversibly catalyzed a ring-opening of α-substituted cyclic acid anhydrides 1 preferentially at the less hindered carbonyl group to give monoesters with high regioselectivity.

Full text of DOI:10.1016/S0040-4039(00)99517-0

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