
Journal of Organic Chemistry p. 3347 - 3353 (1989)
Update date:2022-07-29
Topics:
Ziegler, Frederick E.
Cain, William T.
A synthesis of (+)-carboxylic acid 2a, which has been previously converted into the ionophore (-)-calcimycin (A-23187) and analogues thereof, is described.The synthesis involves the use of (S)-3-methyl-γ-butyrolactone (4) and both enantiomers of allylic alcohol 3a as the chiral entities.
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