Journal of the American Chemical Society p. 6247 - 6256 (1989)
Update date:2022-09-26
Topics: Enantioselective Synthetic route Total synthesis Chiral Pool Synthesis Stereochemical analysis Enantioselective Catalysis 9S-dihydroerythronolide A seco acid
Chamberlin
Dezube
Reich
Sall
A concise and enantioselective total synthesis of 9S-dihydroerythronolide A seco acid(8) is described. The functionalized γ-lactones 9 and 10, which serve as chiral building blocks for the C3-C7 and C9-C15 segments of the seco acid 8, were readily prepare
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