DESIGN AND SYNTHESIS OF SUBSTRATE ANALOGS FOR THE INHIBITION OF DEHYDROQUINATE SYNTHASE

DOI: 10.1016/S0040-4039(00)99490-5

Source and publish data:

Tetrahedron Letters p. 1461 - 1464 (1989)

Update date:2022-08-04

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Authors:

Nikolaides, Nicholas

Ganem, Bruce

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Article abstract of DOI:10.1016/S0040-4039(00)99490-5

The synthesis of two enantiomerically pure substrate analogs, designed as potential inhibitors of dehydroquinate synthase on the basis of the proposed mechanistic pathway for this enzyme, is reported.

Full text of DOI:10.1016/S0040-4039(00)99490-5

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