Journal of Medicinal Chemistry p. 1145 - 1151 (1990)
Update date:2022-07-29
Topics:
Jacobsen, E. Jon
McCall, John M.
Ayer, Donald E.
VanDoornik, Fred J.
Palmer, John R.
et al.
A novel class of 21-aminosteroids has been developed.Compounds within this series are potent inhibitors of iron-dependent lipid peroxidation in rat brain homogenates with IC50's as low as 3 μM.Furthermore, selected members enhance early neurolo
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