Molecules p. 288 - 304 (2010)
Update date:2022-08-04
Topics:
Musiol, Robert
Jampilek, Josef
Nycz, Jacek E.
Pesko, Matus
Carroll, James
Kralova, Katarina
Vejsova, Marcela
O'Mahony, Jim
Coffey, Aidan
Mrozek, Anna
Polanski, Jaroslaw
In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity. They were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four mycobacterial strains and against eight fungal strains. Several compounds showed biological activity comparable with or higher than the standards isoniazid or fluconazole. For all the compounds, the relationships between the lipophilicity and the chemical structure of the studied compounds are discussed.
View MoreJingzhou TianHe Sci&Tech Chemical Co., Ltd.
Contact:86-716-8331612
Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
SJZ Chenghui Chemical Co., Ltd.
Contact:86-311-87713916
Address:no.368 youyi north avenue
NingBO Hong Xiang Biochem.Co.Ltd
website:http://www.hxbiochem.com
Contact:0574-66003444
Address:Ning Bo Bei Lun
Jiangyin Tenghua Import&Export Co.,Ltd.
Contact:+86-510-86263875
Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
TAIXING BEST NEW MATERIALS CO., LTD
Contact:0523-87998158;
Address:No.18 Zhonggang Road,Taixing City ,Jiangsu , China
Doi:10.3390/molecules15107227
(2010)Doi:10.1021/jo101388x
(2010)Doi:10.1002/anie.201001799
(2010)Doi:10.2478/s11696-010-0047-1
(2010)Doi:10.1016/S0040-4039(00)99234-7
(1989)Doi:10.1002/anie.201001729
(2010)