Enantioselective syntheses of (2S,4AS,8aR)-1,1-4a-trimethyldecahydronaphthalen-2-ol[(-)-TMD], (4aS,8aR)-5,58a-trimethyloctahydronaphthalen-2(1H)-one, and (-)-Polywood, through Michael-type reaction of chiral imines

Article abstract of DOI:10.1016/S0957-4166(97)00082-7

The title compounds 6, 15, and 17 have been synthesized in a straightforward way in good yields and high enantiomeric excesses by the chiral imines method, leading to building-blocks 2 and 10, followed by a few conventional steps.