EXTENSION OF THE HORNER-WITTIG REACTION TO THE SYNTHESIS OF E-ALKENES WITH CHIRAL SUBSTITUENTS: STEREOCHEMICAL CONTROL BY ACYL TRANSFER

DOI: 10.1016/S0040-4039(01)80750-4

Source and publish data:

Tetrahedron Letters p. 4581 - 4584 (1989)

Update date:2022-08-04

Topics:

Authors:

Ayrey, Peter M.

Warren, Stuart

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)80750-4

Single crystalline diastereoisomers of hydroxyalkyl phosphine oxides (and hence functionalised E-alkenes) can be isolated, even when other chiral centres are present in the molecule, if they are made by acyl transfer.

Full text of DOI:10.1016/S0040-4039(01)80750-4

Products guided by the article

Product name:1-[(1R,2R)-1-(Diphenyl-phosphinoyl)-2-phenyl-propyl]-cyclohexanol

Cas No:126338-32-7

R&D Labs maybe for 126338-32-7

Ningbo Inno Pharmchem Co., Ltd.

Contact:86-574-87319282

Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Wuhan HengHeDa Pharm Co., Ltd

Contact:86-27-84888681

Address:Wuhan economic & technology development zone
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District
Sinochem Jiangsu Co.,Ltd.

Contact:86-25-51817806

Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china
Improve Medical Technology(Nanxiong) Co., Ltd

Contact:86-751-3836997

Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China

Relevant to this article

Cooperative catalysis in highly enantioselective Mannich-type three-component reaction of a diazoacetophenone with an alcohol and an imine

Doi:10.1039/c0cc03024d
(2011)
Reagent-based DOS: Developing a diastereoselective methodology to access spirocyclic- and fused heterocyclic ring systems

Doi:10.1002/asia.201200385
(2012)
New synthesis of (+)- and (-)-nojirimycin from myo-inositol

Doi:10.1039/c39890001230
(1989)
Synthesis of CF₃-substituted sulfoximines from sulfonimidoyl fluorides

Doi:10.1021/ol103030w
(2011)
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2- hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents

Doi:10.1016/j.ejmech.2010.11.019
(2011)
Quinazoline antifolate thymidylate synthase inhibitors: Replacement of glutamic acid in the C2-methyl series

Doi:10.1021/jm00006a019
(1995)

Article Doi