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Synthesis of acylated active methylene compounds with N-boc-L-phenylalanine and their heterocyclization, both achieved enantioselectively

DOI: 10.1515/HC.2005.11.3-4.325

Source and publish data:

Heterocyclic Communications p. 325 - 329 (2005)

Update date:2022-08-04

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Authors:

Hamilakis, StylianosHamilakis, Stylianos

Tsolomitis, AthanaseTsolomitis, Athanase

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Article abstract of DOI:10.1515/HC.2005.11.3-4.325

Three active methylene compounds, malononitrile, methyl cyanoacetate and Meldrum's acid, have been found to be acylated effectively with N-Boc-L-phenylalanine using carbonyldiimidazole (CDI) activation conditions. Two of the aminoacetyl derivatives isolat

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Full text of DOI:10.1515/HC.2005.11.3-4.325

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Brought to you by | Linnaeus University - Växjö  
Authenticated  
Download Date | 10/12/14 12:47 PM  
Brought to you by | Linnaeus University - Växjö  
Authenticated  
Download Date | 10/12/14 12:47 PM  
Brought to you by | Linnaeus University - Växjö  
Authenticated  
Download Date | 10/12/14 12:47 PM  
Brought to you by | Linnaeus University - Växjö  
Authenticated  
Download Date | 10/12/14 12:47 PM  
Brought to you by | Linnaeus University - Växjö  
Authenticated  
Download Date | 10/12/14 12:47 PM  

Products guided by the article

Product name:Carbamic acid, [3,3-dicyano-2-hydroxy-1-(phenylmethyl)-2-propenyl]-, 1,1-dimethylethyl ester, (S)-

Cas No:126950-13-8

126950-13-8

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