Studies on hindered phenols and analogues. V. Synthesis, identification and antidiabetic activity on the glucuronide of CS-045

DOI: 10.1248/cpb.39.2124

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2124 - 2125 (1991)

Update date:2022-07-29

Topics:

Authors:

Yoshioka

Aizawa Aizawa

Fujita Fujita

Nakamura

Sasahara

Kuwano Kuwano

Kinoshita

Horikoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.2124

The glucuronide of a new oral antidiabetic agent, (±)-5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl]thi azolidine-2,4-dione (CS-045) (1), was synthesized to confirm the structure of a metabolite in monkeys (Macaca fassicularis) and to exa

Full text of DOI:10.1248/cpb.39.2124

NII-Electronic Library Service

Products guided by the article

Product name:methyl 2,3,4-tri-O-acetyl-1-O-<2-<4-<2,4-dioxothiazolidin-5-ylmethyl>phenoxymethyl>-2,5,7,8-tetramethylchroman-6-yl>-β-D-glucopyranuronate

Cas No:127040-00-0

R&D Labs maybe for 127040-00-0

QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Zhejiang Chemicals Import & Export Corporation (ZHECHEM)

Contact:+86-571-87046953

Address:No. 37, Qingchun Road
shandong lukang animal & plant drug trading co.,ltd.

Contact:15853765968

Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china
Anhui Qingyun Pharmaceutical and Chemical Co.,Ltd

Contact:+86-551-63633067

Address:Shuangfeng Road Hefei Anhui
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China

Relevant to this article

Synthesis and anti-fungal activity of seven oleanolic acid glycosides

Doi:10.3390/molecules16021113
(2011)
Directed Nitrile Oxide Cycloaddition Reactions. The Use of Hydrogen Bonding To Direct Regio- and Stereochemistry in Nitrile Oxide Cycloadditions with Cyclopentenylamides

Doi:10.1021/jo00299a004
(1990)
Pseudo-peptides derived from isomannide: Inhibitors of serine proteases

Doi:10.1007/s00726-009-0273-4
(2010)
Preparation of bipyridyl derivatives via α-lithiation of pyridyl phenyl sulfoxides, substitution with electrophiles and cross-coupling reactions with Grignard reagents

Doi:10.1016/S0040-4039(01)93431-8
(1989)
1H and 13C NMR Studies of some O-Carbamoyloximes

Doi:10.1002/mrc.1260271117
(1989)
Stereo- and Enantiospecific Syntheses of (-)-Reiswigins A and B. Assignment of Absolute and Relative Configuration

Doi:10.1021/jo00301a034
(1990)

Article Doi